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For example, a small number of subjects reported the following mild side effects in the course of a four-week glutathione study at the dose of 1g/day [13]: Flatulence Loose stools Flushing Weight gain In a more specialized study involving cystic fibrosis patients and much higher glutathione doses, some of the patients reported tightness in the torso, diarrhea, and fever-like symptoms [14]

We should also pay attention to dosage

Furthermore, probiotic interventions appear to ameliorate inflammatory biomarkers (e.g., C-reactive protein), enhance glycemic control, and improve insulin metabolism in patients with type 2 diabetes or metabolic syndrome (425429), as well as in pregnant women diagnosed with gestational diabetes mellitus (425, 426)

age = 59.8 7.1 years), 28 patients with GPi-DBS (13 women, 15 men, mean s.d